Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinctfrom Astrocytopathy Induced by AQP4-IgG
Posted by Corey Marcath on
Pooled Human Complement Serum from Innovative Research was used in the following study:
Ling Fang, Xinmei Kang, Zhen Wang, Shisi Wang, Jingqi Wang, Yifan Zhou, Chen Chen, Xiaobo Sun, Yaping Yan, Allan G. KermodeLisheng Peng, Wei Qiu
Neuroscience Bulletin
18 January 2019
“...Immunoglobulin G against myelin oligodendrocyte glycoprotein (MOG-IgG) is detectable in neuromyelitis optica spectrum disorder (NMOSD) without aquaporin4 IgG (AQP4-IgG), but its pathogenicity remains unclear. In this study, we explored the pathogenic mechanisms of MOG-IgG in vitro and in vivo and compared them with those of AQP4-IgG. …Human complement (hC) from Innovative Research (IPLA-CSER, Innovative Research, Novi, MI) was stored at - 80 C…”
Related products available from Innovative Research also include:
Single Donor Human Plasma (Blood Derived)