Product References — Human Plasma

Pooled Human AB Serum Plasma Derived Heat Inactivated from Innovative Research was used in the following study:   Human Interleukin-4–Treated Regulatory Macrophages Promote Epithelial Wound Healing and Reduce Colitis in Mouse Model Timothy S. Jayme, Gabriella Leung, Arthur Wang, Matthew L. Workentine, Sruthi Rajeev, Adam Shute, Blanca E. Callejas, Nicole Mancini, Paul L. Beck, Remo Panaccione, Derek M. McKay Science Advances June 5, 2020 Murine alternatively activated macrophages can exert anti-inflammatory effects. We sought to determine if IL-4–treated human macrophages [i.e., hM(IL4)] would promote epithelial wound repair and can serve as a cell transfer treatment for inflammatory bowel disease (IBD)....

Pooled Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Enhanced Phospholipid Isomer Analysis by Online Photochemical Derivatization and RPLC-MS Wenpeng Zhang, Bing Shang, Zheng Ouyang, Yu Xia Analytical Chemistry 4/9/2020 “Mapping the complete molecular composition of a lipidome is considered an important goal of lipidomics for unraveling pathways and mechanisms behind lipid homeostasis. Conventional dissociation methods of mass spectrometry (MS) usually cannot give detailed structural information on lipids such as locations of carbon−carbon double bonds (C=C) in acyl chains... Pooled human plasma was obtained from Innovative Research (Novi, MI, U.S.A.)...”   Related products available...

Single Donor Human Plasma (Blood Derived) and Innovative Grade US Origin Rat Sprague Dawley Single Donor Plasma from Innovative Research was used in the following study:   Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma Snehal K Shukla, Hossam Kadry, Jayshil A Bhatt, Rasha Elbatanony, Fakhrul Ahsan & Vivek Gupta Future Science 13 Feb 2020 “A high throughput ultra-performance liquid chromatography (UPLC)-ultraviolet method for quantification of nintedanib in rat and human plasma was developed and optimized using chemometrical approach… Rat plasma and human plasma were acquired from Innovative...

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   LC-MS/MS analysis of plasma glucosylsphingosine as a biomarker for diagnosis and follow-up monitoring in Gaucher disease in the Spanish population Pilar Irún, Jorge J. Cebolla, Laura López de Frutos, Isabel De Castro-Orós, Mercedes Roca-Espiau and Pilar Giraldo Clinical Chemistry and Laboratory Medicine (CCLM) February 3, 2020 The method was validated according to the guidelines of the US Food and Drug administration [33]. Briefly, matrix effects were assessed by analyzing five repetitions of a mixture of IS and ES in methanol and also spiking the same...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction Amanda M. G. Lobo Igor R. S. Magalhães SSC plus 12/12/2019 “Tafenoquine, a synthetic analogue of primaquine, is a promising agent for the treatment of human malaria since this drug shows better antimalarial activity than primaquine in vitro and short treatment course. There are some methods for the quantification of tafenoquine in plasma, but none uses dispersive-liquid-liquid microextraction, an extraction technique that shows some advantages, such as miniaturization, low cost and high potential for...