(January 6, 2015) Innovative Research's Human Neutrophil Elastase was recently used in the following study:
HNE activity inhibitory bioassay. HNE (EC 3.4.21.37) from human leucocytes was purchased from Innovative Research Company (Novi, Michigan). ONO-5046,HNE substrate (MeOSucAlaAlaProValpNA), soybean...
(January 6, 2015) Innovative Research's Porcine Myoglobin ELISA Kit was recently used in the following study:
... Hb and myoglobin To estimate the contribution of Hb and myoglobin to the total amount of heme proteins, myoglobin concentrations were analyzed by a Porcine Myoglobin ELISA (Innovative Research, Peary Court Novi, MI) according to the manufacturer's instructions.
(January 12, 2015) Innovative Research's Pooled Normal Human Serum was recently used in the following study:
From the 1. Department of Therapeutic Discovery, 2. Department of Process & Product Development, and 3. Therapeutic Innovation Unit of 4Amgen Inc. Pooled normal human serum(cat IPLA-SER) was purchased from Innovative Research, Inc. (Novi, MI).
(January 14, 2015) Innovative Research's Pooled Normal Human Serum was recently used in the following study:
MATERIALS AND METHODS 101 Human serum samples 102 Human serum samples were obtained from Innovative Research (Novi, Michigan) and were collected 103 between March 2012 and April 2013. Samples were pre-screened using HAI assay against wild type 104
(January 15, 2015) Innovative Research's Human Receptor Associated Protein (RAP) was recently used in the following study:
Receptor-associated protein (RAP) was pur- chased from Innovative Research Inc.(Novi, MI, USA), and nu- clear factor k-light-chain-enhancer (NF-kB) inhibitor BAY 117085 from Enzo Life Science (Farmingdale, NY, USA).
(January 20, 2015) Innovative Research's Human Plasminogen Total ELISA Kit was recently used in the following study:
... abbreviated: plasmin(ogen), prostasin and urokinase (uPA) were measured using ELISA kits:plasminogen (Cat IHPLGKT-TOT; Innovative Research, Novi, MI, USA); prostasin (Cat ... The study was funded by Strategic Research (Danish Innovation Foundation), The...
(January 21, 2015) Innovative Research's Pooled Normal Human Serum was recently used in the following study:
Each goldenseal was independently determined to contain 13 mg of hydrastine. Human serum was purchased from Millipore (Bedford, MA) or Innovative Research (Novi, MI). LCMS Optima
(January 25, 2015) Innovative Research's Pooled Normal Human Plasma was recently used in the following study:
Nanopure water was prepared using a Water Pro Plus purification system (Labconco,Kansas City, MO, USA). Blank pooled human plasma was purchased from Innovative Research (Novi, MI, USA). 2.2. Synthesis of DETC-NAC and DIPC-NAC.
(January 28, 2015) Innovative Research's Human IgG-Fractionated Purified was recently used in the following study:
on Vero cells (seeded into 96-well plates) in a similar fashion as for RSV, except after 1 h of incubation with virusliposome mixtures, Vero cells were washed with PBS and incubated in DMEM containing 100 g/mL pooled human IgG (Innovative Research, Novi, MI) for 48 h at...
(January 28, 2015) Innovative Research's Innovative Grade US Origin Balb C Mouse Plasma was recently used in the following study:
Balb/c mouse plasma for stability studies was obtained from Innovative Research (Novi, MI). B1R-targeting peptides were synthesized using solid phase approach on an Aapptec (Louisville, KY) Endeavor 90 peptide synthesizer...
(January 29, 2015) Innovative Research's Single Donor Human Whole Blood was recently used in the following study:
... culture medium for CVD 909 was supplemented with 2, 3-dihydroxybenzoate (DHB) (0.0001%w/v). Whole human blood with sodium heparin anticoagulant was purchased from Innovative Research (Novi, MI, USA). For the buffy coat experiments, fresh blood was obtained from...
(January 30, 2014) Innovative Research's Rabbit Red Blood Cells was recently used in the following study:
interests: JO and KBC are co-inventors on a patent application related to these studies filed by the University of Michigan and the ... The mixtures were then incubated on ice for 15 minutes with 0.5 mls of a 10% solution of rabbit RBCs in PBS (Innovative Research, Novi, MI).
Synthesis and biological evaluation of nigranoic acid esters as novel human neutrophil elastase inhibitors
G Huang, L Feng, B Liu, Y He, Y Li, Y Chen - Natural Product Research, 2015HNE activity inhibitory bioassay. HNE (EC 3.4.21.37) from human leucocytes was purchased from Innovative Research Company (Novi, Michigan). ONO-5046,HNE substrate (MeOSucAlaAlaProValpNA), soybean...
(January 6, 2015) Innovative Research's Porcine Myoglobin ELISA Kit was recently used in the following study:
Meat Juice Is Not a Homogeneous Serological Matrix
C Wallander, J Frssling, I Vgsholm, A Burrells...- Foodborne Pathogens and...... Hb and myoglobin To estimate the contribution of Hb and myoglobin to the total amount of heme proteins, myoglobin concentrations were analyzed by a Porcine Myoglobin ELISA (Innovative Research, Peary Court Novi, MI) according to the manufacturer's instructions.
(January 12, 2015) Innovative Research's Pooled Normal Human Serum was recently used in the following study:
A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism
Z Liu, EC Leng, K Gunasekaran, M Pentony, M Shen - Journal of Biological , 2015From the 1. Department of Therapeutic Discovery, 2. Department of Process & Product Development, and 3. Therapeutic Innovation Unit of 4Amgen Inc. Pooled normal human serum(cat IPLA-SER) was purchased from Innovative Research, Inc. (Novi, MI).
(January 14, 2015) Innovative Research's Pooled Normal Human Serum was recently used in the following study:
Broadly-Neutralizing Anti-Influenza Virus Antibodies: Enhancement of Neutralizing Potency in Polyclonal Mixtures and IgA Backbones
W He, CE Mullarkey, JA Duty, TM Moran, P Palese - Journal of Virology, 2015MATERIALS AND METHODS 101 Human serum samples 102 Human serum samples were obtained from Innovative Research (Novi, Michigan) and were collected 103 between March 2012 and April 2013. Samples were pre-screened using HAI assay against wild type 104
(January 15, 2015) Innovative Research's Human Receptor Associated Protein (RAP) was recently used in the following study:
Different mechanisms of apolipoprotein E isoformdependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2...
X Li, KS Montine, CD Keene, TJ Montine - The FASEB Journal, 2015Receptor-associated protein (RAP) was pur- chased from Innovative Research Inc.(Novi, MI, USA), and nu- clear factor k-light-chain-enhancer (NF-kB) inhibitor BAY 117085 from Enzo Life Science (Farmingdale, NY, USA).
(January 20, 2015) Innovative Research's Human Plasminogen Total ELISA Kit was recently used in the following study:
Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in
H Andersen, UG Friis, PBL Hansen, P Svenningsen - Nephrology Dialysis , 2015... abbreviated: plasmin(ogen), prostasin and urokinase (uPA) were measured using ELISA kits:plasminogen (Cat IHPLGKT-TOT; Innovative Research, Novi, MI, USA); prostasin (Cat ... The study was funded by Strategic Research (Danish Innovation Foundation), The...
(January 21, 2015) Innovative Research's Pooled Normal Human Serum was recently used in the following study:
Hydrastine Pharmacokinetics and Metabolism after a Single Oral Dose of Goldenseal (Hydrastis canadensis) to Humans
PK Gupta, GW Barone, B Gurley, EK Fifer - Drug Metabolism and , 2015Each goldenseal was independently determined to contain 13 mg of hydrastine. Human serum was purchased from Millipore (Bedford, MA) or Innovative Research (Novi, MI). LCMS Optima
(January 25, 2015) Innovative Research's Pooled Normal Human Plasma was recently used in the following study:
N-Acetyl-S-(N, N-diethylcarbamoyl) Cysteine in Rat Nucleus Accumbens, medial Prefrontal Cortex, and in RAT and Human Plasma after Disulfiram Administration
RD Winefield, AAM Heemskerk, S Kaul, TD Williams - Journal of Pharmaceutical , 2015Nanopure water was prepared using a Water Pro Plus purification system (Labconco,Kansas City, MO, USA). Blank pooled human plasma was purchased from Innovative Research (Novi, MI, USA). 2.2. Synthesis of DETC-NAC and DIPC-NAC.
(January 28, 2015) Innovative Research's Human IgG-Fractionated Purified was recently used in the following study:
Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses
GL Hendricks, L Velazquez, S Pham, N Qaisar - Antiviral Research, 2015on Vero cells (seeded into 96-well plates) in a similar fashion as for RSV, except after 1 h of incubation with virusliposome mixtures, Vero cells were washed with PBS and incubated in DMEM containing 100 g/mL pooled human IgG (Innovative Research, Novi, MI) for 48 h at...
(January 28, 2015) Innovative Research's Innovative Grade US Origin Balb C Mouse Plasma was recently used in the following study:
18F-Trifluoroborate Derivatives of Des-Arg10 Kallidin for Imaging Bradykinin B1 Receptor Expression with Positron Emission Tomography
Z Liu, G Amouroux, Z Zhang, J Pan, N Hundal-Jabal - Molecular Pharmaceutics, 2015Balb/c mouse plasma for stability studies was obtained from Innovative Research (Novi, MI). B1R-targeting peptides were synthesized using solid phase approach on an Aapptec (Louisville, KY) Endeavor 90 peptide synthesizer...
(January 29, 2015) Innovative Research's Single Donor Human Whole Blood was recently used in the following study:
Adaptation of red blood cell lysis represents a fundamental breakthrough that improves the sensitivity of Salmonella detection in blood
MA Boyd, SM Tennant, JH Melendez, D Toema… - Journal of Applied …, 2015... culture medium for CVD 909 was supplemented with 2, 3-dihydroxybenzoate (DHB) (0.0001%w/v). Whole human blood with sodium heparin anticoagulant was purchased from Innovative Research (Novi, MI, USA). For the buffy coat experiments, fresh blood was obtained from...
(January 30, 2014) Innovative Research's Rabbit Red Blood Cells was recently used in the following study:
Identification and Validation of a Linear Protective Neutralizing Epitope in the -Pore Domain of Alpha Toxin
J Oscherwitz, KB Cease - PLoS ONE, 2015interests: JO and KBC are co-inventors on a patent application related to these studies filed by the University of Michigan and the ... The mixtures were then incubated on ice for 15 minutes with 0.5 mls of a 10% solution of rabbit RBCs in PBS (Innovative Research, Novi, MI).
