Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model
Posted by Adam Awdish on
Rat Active tPA ELISA Kit and Rat Active PAI-1 ELISA Kit from Innovative Research were used in the following study:
Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model
Anna Gromotowicz-Poplawska, Piotr Szoka, Agnieszka Zakrzeska, Patrycjusz Kolodziejczyk, Natalia Marcinczyk, Janusz Szemraj, Piotr Tutka, and Ewa Chabielska
Cells
February 22, 2021
According to evidence gathered in studies over recent years, there appears to be a link between the activation of the renin–angiotensin–aldosterone system (RAAS) and potentially severe cardiovascular problems. The primary process responsible for these cardiac events is acute intravascular arterial thrombosis.
The final product of the RAAS system, Aldosterone (ALDO), plays a role in the pathogenesis of cardiovascular diseases. In fact, high levels of ALDO were found to be associated with an increase in total mortality, risk of acute cardiac event, and more. In this study, researchers investigated the role of ALDO in the development of arterial thrombosis in rat models.
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