Product References — Innovative Grade US Origin Mouse CD1 Plasma

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   An Effective and Safe Enkephalin Analog for Antinociception K. K. DurgaRao Viswanadham, Roland Böttger, Lukas Hohenwarter, Anne Nguyen, Elham Rouhollahi, Alexander Smith, Yi-Hsuan Tsai, Yuan-Yu Chang, Christopher Llynard Ortiz, Lee-Wei Yang, Liliana Jimenez, Siyuan Li, Chan Hur, and Shyh-Dar Li Pharmaceutics June 22, 2021 Many injuries and diseases may lead to patients experiencing acute pain as a symptom, and a majority of surgery and trauma patients experience severe or intolerable pain that has the potential to result in chronic pain. Chronic pain is...

Innovative Grade US Origin Mouse CD1 Plasma and Pooled Human Plasma Apheresis Derived from Innovative Research were used in the following study:   Can Remdesivir and its Parent Nucleoside GS-441524 be Potential Oral Drugs? An in vitro and in vivo DMPK Assessment Jiashu Xie, Zhengqiang Wang Acta Pharmaceutica Sinica B March 5, 2021 To date, the only FDA-approved drug for treating COVID-19 is Remdesivir (RDV), which can only be administered intravenously. RDV is a ProTide drug derived from nucleoside GS-441524, and the potency of RDV is dependent on intracellular conversion into GS-441524 triphosphate. In vitro studies of RDV in human...

Innovative Grade US Origin Mouse CD1 Plasma from Innovative Research was used in the following study:   Combined maternal exposure to cypermethrin and stress affect embryonic brain and placental outcomes in mice Benjamin A. Elser, Khaled Kayali, Ram Dhakal, Bailey O’Hare, Kai Wang, Hans Joachim Lehmler, and Hanna E. Stevens Toxicological Sciences 19 March 2020 “Prenatal exposure to cypermethrin is a risk factor for adverse neurodevelopmental outcomes in children. In addition, maternal psychological stress during pregnancy has significant effects on fetal neurodevelopment and may influence end-stage toxicity to offspring by altering maternal xenobiotic metabolism…untreated mouse plasma (Innovative Research, Novi, MI,...

CD-1 Mouse Plasma from Innovative Research was used in the following study:   Design, synthesis and evaluation of 111In labeled DOTA-conjugated tetrapeptides having high affinity and selectivity for mu opioid receptors John R. Lever, Emily A.Fergason-Cantrell, Terry L. Carmack, Lisa D. Watkinson, Fabio Gallazzi Nuclear Medicine and Biology Volume 70, March 2019, Pages 53-66 "... Peripheral mu (μ) opioid receptors are implicated in pain, bowel dysfunction and the progression of certain cancers. In an effort to identify radioligands well suited for imaging these peripheral sites, we have prepared and evaluated four hydrophilic [111In]-labeled, DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) conjugated μ tetrapeptides. ......

Mouse Plasma from Innovative Research was used in the following study:   Orally Available Near Infrared Imaging Agents for the Early Detection of Diseases Sumit Bhatnagar University of Michigan 2018 "... Mouse plasma (Innovative Research) was mixed with either 20 µM BODIPY FL, 50 µM of Hoechst dye, or 1 µM for Integrisense 680. After equilibration, the buffer in each chamber was adjusted to 50/50 mouse plasma and PBS to eliminate effects of protein binding on fluorescence. ..."   Related products available from Innovative Research also include: Innovative Grade US Origin Mouse Balb C Plasma Innovative Grade US Origin Mouse...