Mouse Factor II (Prothrombin) Purified

Select this product for Molecular Innovations name, Mouse Prothrombin and product number, MFII.Mouse Factor II (Prothrombin) Purified from Innovative Research has been purified from US origin mouse plasma. This is a frozen liquid buffered in 100 mM Tris-HCl/0.15 M NaCl/pH 7.4, and a purity of greater than 95% as determined by SDS-PAGE analysis (showing no reduction when incubated with 2-mercaptoethanol).Prothrombin (Coagulation Factor II) is converted to active Thrombin (FIIa) during the coagulation cascade. This happens when Factor Xa and its cofactor, Factor V, together cleave Prothrombin in two, creating a fragment (fragment 1.2, which is formed from the N-terminal Gla domain and two Kringle domains of Prothrombin) and thrombin (containing only the serine protease domain).More Details: Source: Mouse Plasma Purification: Chromatographically purified Purity: >95% by SDS-PAGE Storage Conditions: -60 to -80C For research use only. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.