Case Studies

Within the world of in vitro research, various important biological samples such as human plasma or serum play a crucial role in studying cellular functions, disease mechanisms, and therapeutic interventions. Among the various terms researchers encounter, "depleted" and "deficient" are often used to describe samples lacking specific components. While they may seem similar, or even interchangeable, at first glance, these terms have distinct meanings and applications. Understanding their differences is vital for selecting the right samples for your experiments.   What is a Depleted Sample? A depleted sample has undergone artificial processing to remove a specific component or set of...

The Innovative Research lab pulled together an explainer on one of our recently popular monoclonal antibodies to assist with your discoveries. Monoclonal antibodies are generated to target specific proteins within the body. MA-1H10 binds and blocks the Very-Low-Density Lipoprotein Receptor (VLDLR), a protein involved in lipid metabolism and potentially implicated in various health conditions. In this explainer, we'll delve into the significance of MA-1H10 and its potential applications.What is VLDLR? VLDLR, or Very-Low-Density Lipoprotein Receptor, is a protein found on the surface of cells, primarily in tissues like the liver, heart, and adipose (fat) tissue. Its main function is to...

Hemophilia is a bleeding disorder in which the body is unable to form blood clots properly, which can lead to problems like spontaneous bleeding and excessive bleeding upon injury. This disorder is caused by a genetic deficiency in one of the proteins associated with the coagulation cascade, a series of reactions that leads to the formation of a stable blood clot. When the body is attempting to form a clot, this cascade comes to a halt when the protein responsible for the next step in the chain is missing; as a result, the clot is unable to form as it...