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Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Posted by Corey Marcath on

Pooled Human Urine and Pooled Human Serum Off The Clot from Innovative Research was used in the following study:

 

Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Alex J. Rai Kevin A. Schug, Katarína Maráková

Journal of Separation Science
2/7/2020

“In biological systems, variable protein expression is a crucial marker for numerous diseases, including cancer. The vast majority of liquid chromatography–triple quadrupole mass spectrometry-based quantitative protein assays use bottom-up methodologies, where proteins are subjected to proteolytic cleavage prior to analysis. …As biological matrices, pooled human urine and pooled human serum were purchased from Innovative Research (Novi, MI, USA)...”

 

Related products available from Innovative Research also include:

  • Tags: Human Biological Fluids, Human Serum, Pooled Human Serum Off The Clot, Pooled Human Urine

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