Synthesis of gold nanocluster-loaded lysozyme nanoparticles for label-free ratiometric fluorescent pH sensing: applications to enzyme–substrate systems and cellular imaging
“…Intracellular pH is one of the most indispensable factors for the function and metabolism processes of a cell, such as cell membrane polarity, cellular signaling, vesicle trafficking, cell volume regulation, cell proliferation and apoptosis.. …For the determination of the urea level in real-world samples, pooled normal human plasma was purchased from InnovativeResearch (Novi, MI, USA)…”
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