Snake Venom Phosphodiesterase I Purified lyophilized from Innovative Research is prepared by process of Williams, Sung and Laskowski, JBC, 236, 1130 (1961) and treated to inactivate contaminating 5Æ-nucleotidase activity according to Sulkowski and Laskowski, Biochim. Biophys. Acta, 240, 443 (1961). This is a lyophilized in vials. This product is useful successively hydrolyzing 5Æ-mononucleotides from 3Æ-OH-terminated riboand deoxyribo-oligonucleotides. The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. Phosphodiesterase is inhibited by reducing agents such as glutathione, The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. It is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids and completely inhibited by 5 mM EDTA. ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+. More Details: Source: Rattlesnake Venom Storage Conditions: -20░C Please note ¢ this product replaces our old product number IRWBE0012 (same product, new number). At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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