Suppression of Choroidal Neovascularization and Fibrosis by a Novel RNAi Therapeutic Agent against (Pro)renin Receptor
Posted by Corey Marcath on
Human Prorenin Native Recombinant from Innovative Research was used in the following study:
Ye Liu, Atsuhiro Kanda, Di Wu, Erdal Tan Ishizuka, Satoru Kase, Kousuke Noda, Atsuhiro Ichihara, and Susumu Ishida
Molecular Therapy Nucleic Acids
May 28, 2019
”…Age-related macular degeneration (AMD) is the leading cause of irreversible blindness worldwide.1 The wet (neovascular or exudative) type of AMD usually causes severe vision loss and is characterized by choroidal neovascularization (CNV), which extends from the choroid into the subretinal space and disrupts Bruch’s membrane and the retinal pigment epithelium (RPE). …human recombinant prorenin protein from Innovative Research (Novi, MI, USA), and ERK1/2 inhibitor (U0126) from Promega...”
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