News — PAI-1
As the year 2023 ends, we at Innovative Research want to thank you for your continued support and trust in our products and services. We are proud to be your partner in advancing scientific knowledge and innovation. To show our appreciation, we have prepared some amazing end-of-year promotions that you don’t want to miss. These promotions are designed to help you save time, money, and resources in your lab, while providing you with the highest quality biological samples and reagents for your research needs. Here are the 5 end-of-year promotions that you can take advantage of right now: Ready-to-Ship Repository:...
- Tags: academic research, Animal Plasma, Animal Serum, Animal Whole Blood, Antibodies, Human Biological Fluids, Human Cancer-State, Human Plasma, Mice, Mosue Balb C Plasma, mouse, Mouse Balb C Serum, Mouse C57BL6 Serum, mouse models, mouse plasma, news & updates, PAI-1, Pooled Human Complement Serum, Pooled Human Plasma (Blood Derived), Single Donor Human Plasma Whole Blood Derived, special offers
A genetic mutation in SERPINE1, the gene responsible for Plasminogen Activator Inhibitor-1 (PAI-1), seems to have ties back to leading a longer, healthier life. While complete PAI-1 deficiency can lead to a life-threatening clotting disorder, individuals who were heterozygous for this mutation seem to enjoy an extended lifespan on average.
- Tags: academic research, PAI-1
New research validates the PAI-1 knockout mouse as a preclinical genetic model of human depression, while demonstrating that this knockout also serves as a model for antidepressant resistance. Not only that, but this new research shows PAI-1 is involved in depression separately from the tPA-BDNF axis. As a result, PAI-1 could be a novel target for developing new treatments for major depressive disorder.
- Tags: academic research, PAI-1
- Tags: Antigen Abbreviated, PAI-1