Product References — Human Biological Fluids

Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Posted by Corey Marcath on

Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Pooled Human Urine and Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins Alex J. Rai Kevin A. Schug, Katarína Maráková Journal of Separation Science 2/7/2020 “In biological systems, variable protein expression is a crucial marker for numerous diseases, including cancer. The vast majority of liquid chromatography–triple quadrupole mass spectrometry-based quantitative protein assays use bottom-up methodologies, where proteins are subjected to proteolytic cleavage prior to analysis. …As biological...

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Abnormal LAMP1 glycosylation may play a role in Niemann-Pick disease, type C pathology

Posted by Corey Marcath on

Abnormal LAMP1 glycosylation may play a role in Niemann-Pick disease, type C pathology

Single Donor Human Cerebrospinal Fluid (CSF) from Innovative Research was used in the following study:   Abnormal LAMP1 glycosylation may play a role in Niemann-Pick disease, type C pathology Niamh X. Cawley ,Caitlin Sojka ,Antony Cougnoux,Anna T. Lyons,Elena‐Raluca Nicoli,Christopher A. Wassif,Forbes D. Porter PLOS ONE January 30, 2020 “…A hallmark of Niemann-Pick disease, type C (NPC) is the progressive degeneration of Purkinje neurons in the cerebellum caused by the accumulation of free cholesterol and glycosphingolipids in the lysosome. Recent studies suggest that the state of glycosylation of lysosomal membrane proteins may play a role in disease progression. Our study has...

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Reactive Olfaction Ambient Mass Spectrometry

Posted by Corey Marcath on

Reactive Olfaction Ambient Mass Spectrometry

Single Donor Human Urine from Innovative Research was used in the following study:   Reactive Olfaction Ambient Mass Spectrometry Dmytro S. Kulyk, Taghi Sahraeian, Qiongqiong Wan, and Abraham K. Badu-Tawiah Analytical Chemistry 28 Apr 2019 “…Chemical ionization of organic compounds with negligible vapor pressures (VP) is achieved at atmospheric pressure when the proximal sample is exposed to corona discharge. …Normal single donor human urine was acquired from Innovative Research (Novi, MI,USA)…”   Related products available from Innovative Research also include: Single Donor Human Urine Pooled Human Urine Single Donor Pediatric Human Urine

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Flow injection tyrosinase biosensor for direct determination of acetaminophen in human urine

Posted by Corey Marcath on

Flow injection tyrosinase biosensor for direct determination of acetaminophen in human urine

Pooled Human Urine from Innovative Research was used in the following study:   Flow injection tyrosinase biosensor for direct determination of acetaminophen in human urine Arbër Frangu, Kateřina Pravcová, Petra Šilarová, Tahir Arbneshi, Milan Sýs Analytical and Bioanalytical Chemistry 18 March 2019 ”An amperometric biosensor compatible with a flow injection analysis (FIA) for highly selective determination of acetaminophen (APAP) in a sample of human urine was developed. This biosensor is also suitable for use in the routine pharmaceutical practice. …Commercially available pooled normal human urine(50 mL) was purchased from Innovative Research, Inc. (Novi, USA)…”   Related products available from Innovative...

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