Product References — Rat Sprague Dawley Plasma

Innovative Grade US Origin Rat Sprague Dawley Plasma and Pooled Human Plasma (Blood Derived) from Innovative Research were used in the following study:   Oligo(Lactic Acid)8-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer Lauren Repp, Christopher J. Unterberger, Zhengqing Ye, John B. Feltenberger, Steven M. Swanson, Paul C. Marker and Glen S. Kwon Nanomaterials October 17, 2021 Despite the progress medical science has made over the years in the field of cancer treatment, chemotherapy remains to be one of the most common methods used to combat cancer. An issue that various anticancer drug classes still face, however, is that many of...

Rat Sprague Dawley Plasma from Innovative Research was used in the following study:   Oligo(Lactic Acid)8-Rapamycin Prodrug-Loaded Poly(Ethylene Glycol)-block-Poly(Lactic Acid) Micelles for Injection Yu Tong Tam, Lauren Repp, Zhi-Xiong Ma, John B. Feltenberger, Glen S. Kwon Springer US 19 March 2019 ”…The mammalian target of rapamycin (mTOR) is part of an elaborate intracellular signaling network that is commonly dysregulated in human tumors, making it an attractive substrate for targeted anticancer therapies. Downstream from the PI3K/ AKT signaling pathway, mTOR plays a key role in cell growth, cell proliferation and angiogenesis. …Heparinized Sprague-Dawley rat plasma was purchased from Innovative Research Inc....

Mouse CD1 Plasma, Rat Plasma, and Pooled Human Plasma from Innovative Research were used in the following study:   Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound Lara Pes, Stephan David Koester, Johannes Pall Magnusson, Serghei Chercheja, Federico Medda, Khalid Abu Ajaj, Didier Rognan, Steffen Daum, Friederike Inga Nollmann, Javier Garcia Fernandez, Patricia Perez Galan, Heidi-Kristin Walter, Anna Warnecke, Felix Kratz Journal of Controlled Release Volume 296, 28 February 2019, Pages 81-92 "... AE-KetoSulf07 and AE-Ester-Sulf07 are novel acid-sensitive albumin-binding prodrugs demonstrating tumor regressions in all of the evaluated human tumor xenograft...

Innovative Research's Sprague Dawley Rat Plasma was recently used in the following study: Effects of short-term portacaval anastomosis on the peripheral and brain disposition of the blood-brain barrier permeability marker sodium fluorescein in rats IH Shaik, MK Miah, U Bickel, R Mehvar - Brain Research, 2013...The effects of various bile acids on the f u of FL in plasma were investigated in an in vitro study. Drug-free, heparinized rat plasma (Innovative Research, Novi, MI) was spiked with LCA, CA, CDCA, or TCA at concentrations of 0, 18.75, 37.5, 75, or 150 M.

Innovative Research's Sprague Dawley Rat Plasma was recently used in the following study: Pharmacokinetics and metabolism of (R, R)-methoxyfenoterol in ratD Siluk, DE Mager, HS Kim, Y Wang... - ..., 2010 - informahealthcare.com...Pittsburgh, PA, USA). Purified water was prepared using a Milli-Q system (Millipore, Milford, MA, USA). Control rat plasma and urine were purchased from Innovative Research (Novi, MI, USA). Waymouth 752 culture medium...