Product References — Innovative Grade US Origin Mouse C57BL6 Plasma

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   A Very Long-Acting IL-15: Implications for the Immunotherapy of Cancer John A. Hangasky, Wei Chen, Sigrid Dubois, Anusara Daenthanasanmak, Jürgen Müller, Ralph Reid, Thomas A. Waldmann, and Daniel V. Santi Journal for Immunotherapy of Cancer January 31, 2022 Interleukin-15 (IL-15) is a protein essential for maintenance and survival of natural killer (NK) and CD8+ T cells, making it an interleukin of interest as an immune-oncology agent. IL-2 and IL-15 both bind to NK and CD8+ T cells, however, regulatory T cells are primarily...

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   Sugar Shock: Probing Streptococcus Pyogenes Metabolism Through Bioluminescence Imaging Richard W. Davis IV, Charlotte G. Muse, Heather Eggleston, Micaila Hill, Peter Panizzi bioRxiv January 16, 2022 Despite having limited use in diagnostic medical settings, light-producing bacterium can be extremely useful in pre-clinical experiments by giving the opportunity to track in real-time the spread of these pathogens throughout the course of an infection. A major limitation to using these pathogens in research, however, is the gap in understanding the changes in light production observed...

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   An Effective and Safe Enkephalin Analog for Antinociception K. K. DurgaRao Viswanadham, Roland Böttger, Lukas Hohenwarter, Anne Nguyen, Elham Rouhollahi, Alexander Smith, Yi-Hsuan Tsai, Yuan-Yu Chang, Christopher Llynard Ortiz, Lee-Wei Yang, Liliana Jimenez, Siyuan Li, Chan Hur, and Shyh-Dar Li Pharmaceutics June 22, 2021 Many injuries and diseases may lead to patients experiencing acute pain as a symptom, and a majority of surgery and trauma patients experience severe or intolerable pain that has the potential to result in chronic pain. Chronic pain is...

Innovative Grade US Origin Mouse C57BL6 Plasma and Pooled Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Combined Thrombogenic Effects of Vessel Injury, Pregnancy and Procoagulant Immune Globulin Administration in Mice Yanqun Xu, Yideng Liang, Leonid Parunov, Daryl Despres, Michael Eckhaus, Dorothy Scott, Mikhail Ovanesov & Evi B. Struble Thrombosis Journal November 7, 2020 Normal pregnancies create hypercoagulable conditions within the body to naturally lower the risk of bleeding during birth. However, the changes observed in the hemostatic system also put pregnant women at risk of various thrombotic events (TEs), such as deep venous...

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   In Vitro and In Vivo Comparison of Curcumin-Encapsulated Chitosan-Coated Poly(lactic-co-glycolic acid) Nanoparticles and Curcumin/Hydroxypropyl-β-Cyclodextrin Inclusion Complexes Administered Intranasally as Therapeutic Strategies for Alzheimer’s Disease Li Zhang, Shili Yang, Ling Rong Wong, Hui Xie, and Paul Chi-Lui Ho Molecular Pharmaceutics October 21, 2020 In 2018, the World Alzheimer Report stated that there were about 50 million Alzheimer’s disease (AD) patients worldwide, and they further estimated that the number of AD patients would reach 100 million by 2050. Some of the primary characteristics of AD...