Product References — Human Serum

Pooled Human Serum from Innovative Research was used in the following study:   Supramolecular Polymeric Assemblies for the Selective Depletion of Abundant Acidic Proteins in Serum Mahalia A. C. Serrano, Jingjing Gao, Katrina A. Kelly, Sankaran Thayumanavan, and Richard W. Vachet ACS: Applied Materials & Interfaces Biological and Medical Applications of Materials & Interfaces, Nov 2018 "... The analysis of low-level protein biomarkers in serum is precluded by the presence of other highly abundant serum proteins. Hence, the preliminary removal of serum albumin along with other abundant proteins in serum (i.e. immunoglobulins, transferrin, haptoglobin, alpha-2-macroglobulin and apolipoproteins), is often a...

Human Complement from Innovative Research was used in the following study:   Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica Tianjiao Duan, Alex J. Smith and Alan S. Verkman Journal of Neuroinflammation, October 2018 "... Specified concentrations of AQP4-IgG (or control human IgG, Thermo Fisher Scientific, Rockford, IL) and human complement (Innovative Research, Novi, MI) were added in Hank’s buffer, and cells were incubated at 37 °C for specified times. In some experiments, cells were exposed to serum of an AQP4-IgG seropositive NMO patient who met the revised diagnostic criteria for clinical disease. A fixable dead-cell stain (amine-reactive dye,...

Human Complement Serum from Innovative Research was used in the following study:   Daratumumab binds to mobilized CD34+ cells of myeloma patients in vitro without cytotoxicity or impaired progenitor cell growth Xun Ma, Sandy W. Wong, Ping Zhou, Chakra P. Chaulagain, Parul Doshi, Andreas K. Klein, Kellie Sprague, Adin Kugelmass, Denis Toskic, Melissa Warner, Kenneth B. Miller, Lisa Lee, Cindy Varga and Raymond L. Comenzo Experimental Hematology & Oncology, October 2018 "... Complement-rich human serum (CRHS) was from Innovative Research (Novi, MI), was aliquoted, cryopreserved and thawed for immediate use. For CDC studies, cells were aliquoted at 4 × 105 per well,...

Pooled Human Serum from Innovative Research was used in the following study:   Development of novel aptamers for low-density lipoprotein particle quantification Daniel Klapak, Sarah Broadfoot, Gregory Penner Anup Singh, Eshwar Inapuri PLOS|ONE, October 2018 "... LDL particles were isolated from normal pooled human serum (Innovative Research, Novi, MI) using an established ultracentrifugation protocol [19]. Briefly, three different density solutions (1.006 g/mL, 1.02 g/mL and 1.065 g/mL) of KBR were prepared to enable the separation of the two layers of LDL (LF- and SD-LDL), which fall at the junction between each layer. The visualization (Fig 1) of the LDL heterogeneity was...

Pooled Human Charcoal Dextran Stripped Serum from Innovative Research was used in the following study:   Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells Soo-Yeon Ahn, Mun Seok Jo, Dahae Lee, Seon-Eun Baek, Jiwon Baek, Jae Sik Yu, Jeyun Jo, Hwayoung Yun, Ki Sung Kang, Jeong-Eun Yoo, Ki Hyun Kim Bioorganic ChemistryOctober 2018 (Volume 83, March 2019, Pages 135-144) "... ER-positive MCF-7 human breast cancer cells were seeded in 24- well plates (2 × 104 cells per well) in RPMI1640 medium supplemented with 10% FBS, 100 μg/mL streptomycin, and...