Product References — Proteins

Scientists and researchers are constantly seeking high-quality, reliable tools to advance their studies and push forward our understanding of complex biological systems. At Innovative Research, we understand the pivotal role that native proteins play in your research endeavors. Today, we're excited to showcase some of our most requested native proteins, meticulously isolated and purified in our state-of-the-art facility in Novi, Michigan, and how they can benefit your studies. Immunoglobulin G (IgG): Unlocking Insights into Immune Function Immunoglobulin G, or IgG, represents a significant portion of serum antibodies in humans, making it a cornerstone in immunology research. Our extensive range of...

Human Neutrophil Elastase Purified Lyophilized from Innovative Research was used in the following study:   Neutrophil Elastase Aggravates Periodontitis by Disrupting Gingival Epithelial Barrier via Cleaving Cell Adhesion Molecules Takumi Hiyoshi, Hisanori Domon, Tomoki Maekawa, Hikaru Tamura, Toshihito Isono, Satoru Hirayama, Karin Sasagawa, Fumio Takizawa, Koichi Tabeta, Yutaka Terao Scientific Reports May 17, 2022 Neutrophil elastase (NE) is a proteinase found abundantly in the azurophilic granules of neutrophils. NE is an indicator of neutrophil activity and acts as a host defense mechanism against pathogens by degrading microbiological components during phagocytosis. Excessive NE activity, however, is undesirable because NE can destroy...

Human Factor X Purified from Innovative Research was used in the following study:   Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays M. F. A. Karel, T. P. Lemmens, B. M. E. Tullemans, S. J. H. Wielders, E. Gubbins, D. Van Beurden, S. Van Rijt, and J. M. E. M. Cosemans Cellular and Molecular Bioengineering October 11, 2021 Atherothrombotic events, such as stroke or myocardial infarction, caused by plaque disruption resulting in the exposure of plaque constituents to blood remain a major cause of death in the western world to this day. The combination of plaque constituents and flowing...

Rabbit tPA Recombinant Active from Innovative Research was used in the following study:   Tissue Plasminogen Activator Effects on Fibrin Volume and the Ocular Proteome in a Juvenile Rabbit Model of Lensectomy Jonathon B. Young; Amanda Rae Buchberger; Joseph D. Bogaard; Linda Berg Luecke; Matthew Runquist; Christine M. B. Skumatz; Iris S. Kassem Translational Vision Science & Technology December 2021 Despite advances in the ability to treat cataracts over the years, children with cataracts and pediatric patients suffering from Uveitis tend to express increased inflammation and fibrin scarring following intraocular surgery. This exaggerated immune response following operation has the potential...

Human Factor XII Purified, Human Kallikrein Purified, and Human Prekallikrein Purified from Molecular Innovations were used in the following study:   Identification of the Factor XII Contact Activation Site Enables Sensitive Coagulation Diagnostics Marco Heestermans, Clément Naudin, Reiner K. Mailer, Sandra Konrath, Kristin Klaetschke, Anne Jämsä, Maike Frye, Carsten Deppermann, Giordano Pula, Piotr Kuta, Manuel A. Friese, Mathias Gelderblom, Albert Sickmann, Roger J. S. Preston, Jerzy-Roch Nofer, Stefan Rose-John, Lynn M. Butler, Ophira Salomon, Evi X. Stavrou, and Thomas Renné Nature Communications September 22, 2021 Blood coagulation is an essential part of stopping bleeding at the site of vascular injuries....