Product References — Proteins

Innovative Research's Human HMW Urokinase Fluorescein Labeled was recently used in the following study: A New Class of Orthosteric uPAR uPA Small-Molecule Antagonists Are Allosteric Inhibitors of the uPAR Vitronectin InteractionD Liu, D Zhou, B Wang, WE Knabe, SO Meroueh - ACS chemical biology, 2015incubated with different concentration of 7 (45 mins, room temperature) prior to addition of 40 nM of FITC- conjugated HMW-uPA (Innovative Research, Novi, MI) and allowed to incubate for 30 mins at room temperature.

Innovative Research's Chromogenic Substrate For Plasmin was recently used in the following study: Endogenous plasminogen activators mediate progressive intracranial hemorrhage after traumatic brain injuryN Hijazi, RA Fanne, R Abramovich, S Yarovoi, M Higazi… - Blood, 2015WT-tPA (50 nM) or WT-uPA (5 nM) was incubated with plasminogen (500 nM) and the chromogenic substrate of plasmin S-2251 (Innovative Research, Inc. Novi, MI) (100 µM) alone or in the presence of tPA-S481A (100 nM) or tranexamic acid (1 µM).

Innovative Research's Human Neutrophil Elastase was recently used in the following study: Improved production of sublancin via introduction of three characteristic promoters into operon clusters responsible for this novel distinct glycopeptide biosynthesisS Ji, W Li, AR Baloch, M Wang, B Cao - Microbial Cell Factories, 2015Aliquots of 5 mg/L sublancin in PBS (pH 7.4) were treated under different protease HNE (Innovative Research, Novi, MI), PE (Innovative Research), pepsin (Sigma), V8 (BioCol GmbH), and trypsin (Sigma Chemical Co., St. Louis

Innovative Research's Human IgG-Fractionated Purified was recently used in the following study: Heparin octasaccharide decoy liposomes inhibit replication of multiple virusesGL Hendricks, L Velazquez, S Pham, N Qaisar - Antiviral Research, 2015on Vero cells (seeded into 96-well plates) in a similar fashion as for RSV, except after 1 h of incubation with virusliposome mixtures, Vero cells were washed with PBS and incubated in DMEM containing 100 g/mL pooled human IgG (Innovative Research, Novi, MI) for 48 h at...

Innovative Research's Human Receptor Associated Protein (RAP) was recently used in the following study: Different mechanisms of apolipoprotein E isoformdependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2...X Li, KS Montine, CD Keene, TJ Montine - The FASEB Journal, 2015Receptor-associated protein (RAP) was pur- chased from Innovative Research Inc.(Novi, MI, USA), and nu- clear factor k-light-chain-enhancer (NF-kB) inhibitor BAY 117085 from Enzo Life Science (Farmingdale, NY, USA).