Product References — Human Serum

Pooled Human AB Serum Plasma Derived Heat Inactivated from Innovative Research was used in the following study:   Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production Katrijn Broos, Quentin Lecocq, Brenda De Keersmaecker, Geert Raes, Jurgen Corthals, Eva Lion, Kris Thielemans, Nick Devoogdt, Marleen Keyaerts, and Karine Breckpot Vaccines 7 August 2019 “…Dendritic cell [DC] vaccination is extensively studied as a strategy to activate cancer-specific cytotoxic T lymphocytes [CTLs]. To induce potent anti-tumor CTLs three requirements need to be fulfilled. …CD8pos T cells were plated in triplicate in a 96...

Pooled Human Complement Serum from Innovative Research was used in the following study:   Trimethylamine N-oxide–derived zwitterionic polymers: A new class of ultralow fouling bioinspired materials Bowen Li, Priyesh Jain, Jinrong Ma, Josh K. Smith, Zhefan Yuan, Hsiang-Chieh Hung, Yuwei He, Xiaojie Lin, Kan Wu, Jim Pfaendtner, and Shaoyi Jiang Science Advances 2019 Jun 14 ”…Materials that resist nonspecific protein adsorption are needed for many applications. However, few are able to achieve ultralow fouling in complex biological milieu. Zwitterionic polymers emerge as a class of highly effective ultralow fouling materials due to their superhydrophilicity, outperforming other hydrophilic materials such as...

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Differentiation of 2‐hydroxyglutarate enantiomers and its lactones by gas chromatography/electron ionization tandem mass spectrometry Shinji K. Strain, Morris D. Groves, Mark R. Emmett Rapid Communications in Mass Spectrometry 11 May 2019 “…2‐Hydroxyglutaric acid (2‐hg) is a dicarboxylic acid with a hydroxyl group at the alpha carbon, forming the enantiomers (R)‐2‐ hydroxyglutaric acid (R‐2‐hg) (Figure 1A) and (S)‐2‐hydroxyglutaric acid (S‐2‐hg) (Figure 1B).1 Though detectable in normal tissues, the detection of 2‐hg enantiomers in bodily fluids first gained traction in patients with 2‐hydroxyglutaric acidurias, a...

Pooled Human Complement Serum from Innovative Research was used in the following study:   Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinctfrom Astrocytopathy Induced by AQP4-IgG Ling Fang, Xinmei Kang, Zhen Wang, Shisi Wang, Jingqi Wang, Yifan Zhou, Chen Chen, Xiaobo Sun, Yaping Yan, Allan G. KermodeLisheng Peng, Wei Qiu Neuroscience Bulletin 18 January 2019 “...Immunoglobulin G against myelin oligodendrocyte glycoprotein (MOG-IgG) is detectable in neuromyelitis optica spectrum disorder (NMOSD) without aquaporin4 IgG (AQP4-IgG), but its pathogenicity remains unclear. In this study, we explored the pathogenic mechanisms of MOG-IgG in vitro and in vivo and compared...

Human Serum from Innovative Research was used in the following study:   Development, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for human serum samples Thomas L. Rudge Jr. ,Karen A. Sankovich,Nancy A. Niemuth,Michael S. Anderson,Christopher S. Badorrek,Nick D. Skomrock,Chris M. Cirimotich,Carol L. Sabourin Plos One April 18, 2019 “The need for an efficacious vaccine against highly pathogenic filoviruses was reinforced by the recent and devastating 2014–2016 outbreak of Ebola virus (EBOV) disease in Guinea, Sierra Leone, and Liberia that resulted in more than 10,000 casualties. …The negative control (NC) serum...