Product References — Human Serum
Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins
Posted by Corey Marcath on
Pooled Human Urine and Pooled Human Serum Off The Clot from Innovative Research was used in the following study: Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins Alex J. Rai Kevin A. Schug, Katarína Maráková Journal of Separation Science 2/7/2020 “In biological systems, variable protein expression is a crucial marker for numerous diseases, including cancer. The vast majority of liquid chromatography–triple quadrupole mass spectrometry-based quantitative protein assays use bottom-up methodologies, where proteins are subjected to proteolytic cleavage prior to analysis. …As biological...
Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research
Posted by Corey Marcath on
Pooled Human Serum Off The Clot, Single Donor Human Serum Off The Clot from Innovative Research was used in the following study: Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research Luying Chen, Richard B. van Breemen Journal of Pharmaceutical and Biomedical Analysis 9 November 2019 “To evaluate the potential for interactions between botanical dietary supplements and drug metabolism, Phase I clinical pharmacokinetics studies are conducted using an oral cocktail of probe substrates of cytochrome P450 (CYP) enzymes. A sensitive, specific,...
Evaluation of cryopreservation media for the preservation of human corneal stromal stem cells
Posted by Corey Marcath on
Single Donor Human Serum Off The Clot from Innovative Research was used in the following study: Evaluation of cryopreservation media for the preservation of human corneal stromal stem cells Yuzhao Sun, Aurelie Dos Santos, Alis Balayan, Sophie X. Deng Tissue Engineering December 5, 2019 ”…Human corneal stromal stem cells (CSSCs) have gained increasing attention in the treatment of corneal stromal scars. In view of this, the preparation and storage of CSSCs are critical to maintaining the regenerative potential of CSSCs. The goal of the study was to investigate the human serum (HS) concentration in the cryomedia that could best...
Solid-Phase Microextraction Enables Isolation of BRAF V600E Circulating Tumor DNA from Human Plasma for Detection with a Molecular Beacon Loop-Mediated Isothermal Amplification Assay
Posted by Corey Marcath on
Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study: Solid-Phase Microextraction Enables Isolation of BRAF V600E Circulating Tumor DNA from Human Plasma for Detection with a Molecular Beacon Loop-Mediated Isothermal Amplification Assay Marcelino Varona, Derek R. Eitzmann, Darshna Pagariya, Robbyn K. Anand, and Jared L. Anderson Analytical Chemistry 17 Jan 2020 ”Circulating tumor DNA (ctDNA) is a promising biomarker that can provide a wealth of information regarding the genetic makeup of cancer as well as provide a guide for monitoring treatment. Methods for rapid and accurate profiling of ctDNA are highly desirable in order...
An inherent T cell deficit in healthy males to C. neoformans infection may begin to explain the sex susceptibility in incidence of cryptococcosis
Posted by Corey Marcath on
Pooled Human Serum Off The Clot from Innovative Research was used in the following study: An inherent T cell deficit in healthy males to C. neoformans infection may begin to explain the sex susceptibility in incidence of cryptococcosis Tiffany E. Guess, Joseph Rosen, Natalia Castro-Lopez, Floyd L. Wormley Jr, Erin E. McClelland Biology of Sex Differences 02 September 2019 “…Cryptococcus neoformans is responsible for an estimated 220,000 cases of cryptococcosis, resulting in more than 181,000 deaths each year worldwide. An opportunistic fungal pathogen, C. neoformans typically presents as pneumonia or meningitis, the latter of which is considered an AIDS-defining...